Check Intently (two)pentobarbital will reduce the level or effect of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Strong CYP3A4 inducers may well minimize suvorexant efficacy; if amplified suvorexant dose expected, usually do not exceed 20 mg/daypentobarbital will lower the level or influence of diltiaze… Read More